Applied Therapeutics

General Information


We are a clinical-stage biopharmaceutical company developing a pipeline of novel product candidates against validated molecular targets in indications of high unmet medical need. We focus on molecules and pathways whose role in the disease process is well known based on prior research, but have previously failed to yield successful products due to poor efficacy and tolerability. Our unique approach to drug development leverages recent technological advances to design improved drugs, employs early use of biomarkers to confirm biological activity and focuses on abbreviated regulatory pathways. Our first molecular target is aldose reductase, or AR, an enzyme that converts glucose to sorbitol under oxidative stress conditions, and is implicated in multiple diseases.

Employees: 9
Founded: 2015
Contact Information
Address 340 Madison Avenue, 19th Floor, New York, NY 10173, US
Phone Number (212) 220-9226
Web Address
View Prospectus: Applied Therapeutics
Financial Information
Market Cap $170.5mil
Revenues $0 mil (last 12 months)
Net Income $-16.5 mil (last 12 months)
IPO Profile
Symbol APLT
Exchange NASDAQ
Shares (millions): 4.0
Price range $10.00 - $10.00
Est. $ Volume $40.0 mil
Manager / Joint Managers Citigroup/ Cowen and Company/ UBS Investment Bank
CO-Managers Baird
Expected To Trade: 5/13/2019
Status: Priced
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