General Information

We are a clinical-stage biotechnology company reimagining cell therapy through the development of innovative immunotherapies for patients with cancer and other incurable diseases. We believe cell therapies are one of the forward pillars of medicine, and our mission is to advance humanity by engineering cell therapies that are safer, more effective and more broadly accessible. Though cell therapies have shown benefits to date, cell therapies have historically been constrained to existing biologic structures, which has limited their impact and opportunity. Our novel synthetic binding scaffold, the D-Domain, was engineered to overcome the limitations of traditional Chimeric Antigen Receptor T cells (CAR-Ts). Existing cell therapy solutions, most of which use a biologic-based, single chain variable fragment (scFv) binding domain, tend to be beneficial to a limited segment of patients, often result in high toxicity, and have narrow applicability in treatable indications. We believe we can overcome these limitations by engineering a new class of D-Domain powered autologous and allogeneic CAR-Ts, including classical single infusion CAR-Ts called ddCARs and dosable and controllable universal CAR-Ts called ARC-SparX, to address hematologic cancers, solid tumors, and indications outside of oncology, such as autoimmune diseases.

At the 2021 Annual Meeting of the American Society of Hematology (ASH), we recently announced positive preliminary results from our ongoing Phase 1 clinical trial of CART-ddBCMA, our lead ddCAR product candidate, for the treatment of patients with relapsed or refractory (r/r) multiple myeloma (MM), defined as patients with either minimal response or disease progression within 60 days of last treatment.

(Note: Arcellx, Inc. priced its IPO on Feb. 3, 2022, at $15 – the bottom of its $15-to-$17 range – on 8.25 million shares to raise $123.75 million.)

Industry: Cell therapy - immunotherapies
Employees: 78
Founded: 2014
Contact Information
Address 25 West Watkins Mill Road, Suite A Gaithersburg, MD 20878
Phone Number (240) 327-0603
Web Address
View Prospectus: ARCELLX, INC.
Financial Information
Market Cap $536.64mil
Revenues $0 mil (last 12 months)
Net Income $-53.41 mil (last 12 months)
IPO Profile
Symbol ACLX
Exchange NASDAQ
Shares (millions): 8.3
Price range $15.00 - $15.00
Est. $ Volume $123.8 mil
Manager / Joint Managers BofA Securities/ SVB Leerink/ Barclays/ William Blair
Expected To Trade: 2/4/2022
Status: Priced
Quiet Period Expiration Date:
Lock-Up Period Expiration Date:
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