Orphazyme A/S

General Information

(Note: This is not an IPO, although the company says this is its IPO of ADS in the United States. This is a follow-on offering: It’s an uplisting from the Nasdaq Copenhagen, where, according to the prospectus, the company’s ordinary shares trade under the symbol “ORPHA” and closed on Sept. 17, 2020, at DKK 82.70 per ordinary share, which equals a price of $13.13 per ADS, based on an exchange rate of DKK 6.2967 per $1.00 as of Sept. 17, 2020, and an ADS-to-ordinary share ratio of 1 to 1.)

We are a late-stage biopharmaceutical company harnessing the amplification of Heat Shock Proteins, or HSPs, in order to develop and commercialize novel therapeutics for the treatment of neurodegenerative orphan diseases. In July 2020, we completed a rolling submission of a new drug application, or NDA, for our product candidate, arimoclomol, with the U.S. Food and Drug Administration, or FDA, for Niemann-Pick disease Type C, or NPC, and intend to submit a marketing authorization application, or MAA, to the European Medicines Agency, or EMA, in the second half of 2020. Arimoclomol is also in registrational clinical trials for the treatment of Amyotrophic Lateral Sclerosis, or ALS, and Sporadic Inclusion Body Myositis, or sIBM, and we intend to advance into pivotal-stage clinical development in neurological Gaucher disease.

Arimoclomol is an orally- or naso/gastrically-administered small molecule that crosses the blood-brain barrier and is designed to selectively amplify the natural role of endogenous HSPs, which protect against cellular toxicity caused by protein misfolding, aggregation and lysosomal dysfunction. 

Industry: Pharmaceuticals
Employees: 86
Founded: 2009
Contact Information
Address Ole Maaløes Vej 3, DK-2200 Copenhagen N Denmark
Phone Number +45 39178272
Web Address http://www.orphazyme.com
View Prospectus: Orphazyme A/S
Financial Information
Market Cap $381.3mil
Revenues $0 mil (last 12 months)
Net Income $-88.8 mil (last 12 months)
IPO Profile
Symbol ORPH
Exchange NASDAQ
Shares (millions): 7.6
Price range $11.00 - $11.00
Est. $ Volume $83.8 mil
Manager / Joint Managers BofA Securities/ Cowen and Company/ Guggenheim Securities
CO-Managers Danske Markets
Expected To Trade: 9/29/2020
Status: Priced
Quiet Period Expiration Date:
Lock-Up Period Expiration Date:
SCOOP Rating
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